Biochemistry and Molecular Biology

Showing 1 – 20 of 3835

SORT: Best Match Most Recent Oldest

VIEW: Basic | Expanded

Glaucoma November 2024

Metabolomic Profiling of Open-Angle Glaucoma Etiologic Endotypes: Tohoku Multi-Omics Glaucoma Study

PDF

Akiko Hanyuda; Yoshihiko Raita; Takahiro Ninomiya; Kazuki Hashimoto; Naoko Takada; Kota Sato; Jin Inoue; Seizo Koshiba; Gen Tamiya; Akira Narita; Masato Akiyama; Kazuko Omodaka; Satoru Tsuda; Yu Yokoyama; Noriko Himori; Yasuko Yamamoto; Takazumi Taniguchi; Kazuno Negishi; Toru Nakazawa
TAGS: glaucoma, metabolomics, open-angle glaucoma, multiomics, metabolites
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):44. https://doi.org/10.1167/iovs.65.13.44

Includes: Supplemental Content

Retinal Cell Biology November 2024

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

PDF

Juliane Hammer; Paul Röppenack; Sarah Yousuf; Anja Machate; Marika Fischer; Stefan Hans; Michael Brand
TAGS: adult, zebrafish, phenotype, visual system, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):42. https://doi.org/10.1167/iovs.65.13.42

Includes: Supplemental Content

Retina November 2024

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

PDF

Nicole A. Muench; Heather M. Schmitt; Cassandra L. Schlamp; An-Jey A. Su; Kia Washington; Robert W. Nickells
TAGS: cryopreservation, eye, mice
Trans. Vis. Sci. Tech.. 2024; 13(11):24. https://doi.org/10.1167/tvst.13.11.24

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2024

Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy

PDF

Charkira C. Patrick; Elisa Roztocil; Farha Husain; Steven E. Feldon; Collynn F. Woeller
TAGS: aryl hydrocarbon receptor, fibroblasts, graves' ophthalmopathy, ligands, signal transduction, tapinarof, platelet-derived growth factor, thymidylate synthase, proto-oncogene proteins c-akt
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):40. https://doi.org/10.1167/iovs.65.13.40

Includes: Supplemental Content

Retina November 2024

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

PDF

Saman Ebrahimi; Phillip Bedggood; Yifu Ding; Andrew Metha; Prosenjit Bagchi
TAGS: blood capillaries, blood cells, computer simulation, fluid flow, hematocrit, hemodynamics, microcirculation, microvascular network, velocity, retail clinics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):37. https://doi.org/10.1167/iovs.65.13.37

Includes: Multimedia, Supplemental Content

Biochemistry and Molecular Biology November 2024

Role of Lysyl Oxidase-Like Protein 3 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

PDF

Seung Hyun Park; Soo Hyun Choi; Hyun Young Park; JaeSang Ko; Jin Sook Yoon
TAGS: body tissue, fibroblasts, oxidase, pathogenesis, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):33. https://doi.org/10.1167/iovs.65.13.33

Includes: Supplemental Content

Retina November 2024

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

PDF

Huan Liu; Feiyan Wang; Ziqing Hu; Jing Wei
TAGS: diabetic retinopathy, drug delivery systems, mendelian randomization analysis, plasma proteins, proteins
Trans. Vis. Sci. Tech.. 2024; 13(11):17. https://doi.org/10.1167/tvst.13.11.17

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

PDF

Yanze Yu; Hao Chen; Zhanying Wang; Yuhao Ye; Zhe Zhang; Yongle Bao; Yingnan Jia; Xingtao Zhou; Jing Zhao
TAGS: biochemistry, chronic disease, diabetes mellitus, type 2, myopia, prospective studies, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):26. https://doi.org/10.1167/iovs.65.13.26

Includes: Supplemental Content

Retinal Cell Biology November 2024

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

PDF

Xueming Yao; Ziqi Li; Yi Lei; Qiangyun Liu; Siyue Chen; Haokun Zhang; Xue Dong; Kai He; Ju Guo; Mulin Jun Li; Xiaohong Wang; Hua Yan
TAGS: astrocytes, genes, heterogeneity, mice, multiomics, oxygen, retinal diseases, small nuclear rna, cell communication, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):8. https://doi.org/10.1167/iovs.65.13.8

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2024

Characteristics of Hyaluronan Metabolism During Myofibroblast Differentiation in Orbital Fibroblasts

PDF

Fruzsina R. Papp; Monika Katko; Robert Csiki; Erika Galgoczi; Zsanett Molnar; Annamaria Erdei; Miklos Bodor; Zita Steiber; Bernadett Ujhelyi; Endre V. Nagy
TAGS: fibroblasts, hyaluronan, metabolism, myofibroblasts, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):13. https://doi.org/10.1167/iovs.65.13.13

Glaucoma November 2024

Downregulation of SARM1 Protects Retinal Ganglion Cell Axonal and Somal Degeneration Via JNK Activation in a Glaucomatous Model of Ocular Hypertension

PDF

Xuejin Zhang; Ting Li; Rong Zhang; Junfeng Li; Kaidi Wang; Jihong Wu
TAGS: axon, down-regulation, glaucoma, ocular hypertension, optic nerve, retina, retinal ganglion cells, tissue degeneration, wounds and injuries, injections
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):7. https://doi.org/10.1167/iovs.65.13.7

Includes: Supplemental Content

Immunology and Microbiology November 2024

Age-Associated Alterations in the Metabolome of Human Vitreous in Bacterial Endophthalmitis

PDF

Sreyasi Maiti; Lakshminarayanan Gowtham; Dhanwini Rudraprasad; Vivek P. Dave; Joveeta Joseph
TAGS: bacterial endophthalmitis, endophthalmitis, metabolic disturbance, metabolites, metabolome, vitreous body, metabolomics, older adult
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):6. https://doi.org/10.1167/iovs.65.13.6

Includes: Supplemental Content

Review October 2024

Diffusion Optics Technology (DOT): A Myopia Control Spectacle Lens Based on Contrast Theory

PDF

Jay Neitz; Maureen Neitz
TAGS: lens (device), myopia, optics, lens, crystalline, eye, retina, diffusion, technology
Trans. Vis. Sci. Tech.. 2024; 13(10):42. https://doi.org/10.1167/tvst.13.10.42

Retina October 2024

Roflumilast Attenuates Microglial Senescence and Retinal Inflammatory Neurodegeneration Post Retinal Ischemia Reperfusion Injury Through Inhibiting NLRP3 Inflammasome

PDF

Chunlian Ou; Yiwei Lin; Jing Wen; Hongyang Zhang; Ying Xu; Naiyuan Zhang; Qiong Liu; Yingzi Wu; Jing Xu; Jing Wu
TAGS: aging, inflammasomes, nerve degeneration, nlr family, pyrin domain-containing 3 protein, older adult, reperfusion injury, retinal ischemia, roflumilast, wounds and injuries, microglia
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):38. https://doi.org/10.1167/iovs.65.12.38

Includes: Supplemental Content

Retina October 2024

NMNAT1 Is Essential for Human iPS Cell Differentiation to the Retinal Lineage

PDF

Hiroshi Kuribayashi; Toshiro Iwagawa; Akira Murakami; Takeshi Kawamura; Yutaka Suzuki; Sumiko Watanabe
TAGS: genes, human induced pluripotent stem cells, induced pluripotent stem cells, organoids, proteins, reactive oxygen species, rna, rosiglitazone, western blotting, gene expression
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):37. https://doi.org/10.1167/iovs.65.12.37

Includes: Supplemental Content

Lens October 2024

TiO 2 -Nanoparticle–Enhanced Sonodynamic Therapy for Prevention of Posterior Capsular Opacification and Ferroptosis Exploration of Its Mechanism

PDF

Yuanyuan Li; Pingjun Chang; Liming Xu; Zehui Zhu; Man Hu; Jiaying Cen; Siyan Li; Yun-e Zhao
TAGS: ferroptosis, nanoparticles, opacification, prevention, ultrasonics, sequence analysis, rna
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):24. https://doi.org/10.1167/iovs.65.12.24

Includes: Supplemental Content

Genetics October 2024

Comprehensive Evaluation of the Genetic Basis of Keratoconus: New Perspectives for Clinical Translation

PDF

Miriam Cerván-Martín; Inmaculada Higueras-Serrano; Sara González-Muñoz; Andrea Guzmán-Jiménez; Blas Chaves-Urbano; Rogelio J. Palomino-Morales; Arancha Poo-López; Luis Fernández-Vega-Cueto; Jesús Merayo-Lloves; Ignacio Alcalde; Lara Bossini-Castillo; F. David Carmona
TAGS: genes, genetics, genome-wide association study, keratoconus, polygenic risk score, cohort studies, single nucleotide polymorphism, spanish
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):32. https://doi.org/10.1167/iovs.65.12.32

Includes: Supplemental Content

Glaucoma October 2024

Trabecular Meshwork Abnormalities in a Model of Congenital Glaucoma Due to LTBP2 Mutation

PDF

Odalys Torné; Kazuya Oikawa; Leandro B. C. Teixeira; Julie A. Kiland; Gillian J. McLellan
TAGS: cats, elastic fibers, glaucoma, congenital, mutation, trabecular meshwork, eye, shape, collagen
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):28. https://doi.org/10.1167/iovs.65.12.28

Includes: Supplemental Content

Retina September 2024

Model Predictive Temperature Control for Retinal Laser Treatments

PDF

Viktoria Kleyman; Sophie Eggert; Christian Schmidt; Manuel Schaller; Karl Worthmann; Ralf Brinkmann; Matthias A. Müller
TAGS: body temperature regulation, laser therapy, lasers, process of absorption, temperature, body temperature, eye
Trans. Vis. Sci. Tech.. 2024; 13(9):28. https://doi.org/10.1167/tvst.13.9.28

Cornea September 2024

RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus

PDF

Yunhai Dai; Shilan Mao; Xinyi Zang; Hongqi Ge; Jing Feng; Yalin Wang; Xia Qi; Lingling Yang; Qingjun Zhou; Xiaolei Wang
TAGS: cornea, diabetes mellitus, type 2, human herpesvirus 1, infections, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):36. https://doi.org/10.1167/iovs.65.11.36

Includes: Supplemental Content

1 2 3 4 5

Next 20 Results »

NARROW

Content Type

Journal

Article Type

Topics

Tags

Filters

Specify Date Range

Metabolomic Profiling of Open-Angle Glaucoma Etiologic Endotypes: Tohoku Multi-Omics Glaucoma Study

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

Role of Lysyl Oxidase-Like Protein 3 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

Characteristics of Hyaluronan Metabolism During Myofibroblast Differentiation in Orbital Fibroblasts

Downregulation of SARM1 Protects Retinal Ganglion Cell Axonal and Somal Degeneration Via JNK Activation in a Glaucomatous Model of Ocular Hypertension

Age-Associated Alterations in the Metabolome of Human Vitreous in Bacterial Endophthalmitis

Diffusion Optics Technology (DOT): A Myopia Control Spectacle Lens Based on Contrast Theory

Roflumilast Attenuates Microglial Senescence and Retinal Inflammatory Neurodegeneration Post Retinal Ischemia Reperfusion Injury Through Inhibiting NLRP3 Inflammasome

NMNAT1 Is Essential for Human iPS Cell Differentiation to the Retinal Lineage

TiO 2 -Nanoparticle–Enhanced Sonodynamic Therapy for Prevention of Posterior Capsular Opacification and Ferroptosis Exploration of Its Mechanism

Comprehensive Evaluation of the Genetic Basis of Keratoconus: New Perspectives for Clinical Translation

Trabecular Meshwork Abnormalities in a Model of Congenital Glaucoma Due to LTBP2 Mutation

Model Predictive Temperature Control for Retinal Laser Treatments

RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus

This feature is available to authenticated users only.

Biochemistry and Molecular Biology

To View More...

You must be signed into an individual account to use this feature.