Clinical and Epidemiologic Research

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Clinical and Epidemiologic Research November 2024

Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China

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Dong Liang; Bei Du; Tsz-Wing Leung; Zhuzhu Liu; Qiang Su; Nan Jin; Ziyu Zhang; Mingguang He; Hua Yan; Ruihua Wei; Chea-Su Kee
TAGS: astigmatism, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):45. https://doi.org/10.1167/iovs.65.13.45

Includes: Supplemental Content

Genetics November 2024

Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort

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Mikko Liukkonen; Hanna Heloterä; Leea Siintamo; Bishwa Ghimire; Pirkko Mattila; Niko Kivinen; Joanna Kostanek; Cezary Watala; Maria Hytti; Juha Hyttinen; Ali Koskela; Janusz Blasiak; Kai Kaarniranta
TAGS: cohort studies, finnish, genes, inflammation, oxidative stress, rna, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):30. https://doi.org/10.1167/iovs.65.13.30

Includes: Supplemental Content

Retina November 2024

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

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Huan Liu; Feiyan Wang; Ziqing Hu; Jing Wei
TAGS: diabetic retinopathy, drug delivery systems, mendelian randomization analysis, plasma proteins, proteins
Trans. Vis. Sci. Tech.. 2024; 13(11):17. https://doi.org/10.1167/tvst.13.11.17

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Potential Prognostic Protein Biomarkers in Tears From Noninfectious Uveitis Patients Under Biologic Treatment as a Prelude to Personalized Medicine

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Lorena Rodríguez-Martínez; Carmen Antía Rodríguez-Fernández; Olalla Rodríguez Lemos; Begoña de Domingo; Pere García Bru; Jesús Mateos; Anxo Fernández-Ferreiro
TAGS: biological markers, proteins, tumor necrosis factors, uveitis, individualized medicine, patient prognosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):29. https://doi.org/10.1167/iovs.65.13.29

Includes: Supplemental Content

Genetics November 2024

Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort

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Yufei Xu; Xiao Liu; Nan Wu; Yanling Long; Jiayun Ren; Yu Wang; Xinyi Su; Zengping Liu; Yu Fujinami-Yokokawa; Kaoru Fujinami; Fang Chen; Xiaohong Meng; Yong Liu
TAGS: cohort studies, crystal structure, disease progression, eye, fovea centralis, longitudinal studies, genotype, vision, blindness, mutation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):27. https://doi.org/10.1167/iovs.65.13.27

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

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Yanze Yu; Hao Chen; Zhanying Wang; Yuhao Ye; Zhe Zhang; Yongle Bao; Yingnan Jia; Xingtao Zhou; Jing Zhao
TAGS: biochemistry, chronic disease, diabetes mellitus, type 2, myopia, prospective studies, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):26. https://doi.org/10.1167/iovs.65.13.26

Includes: Supplemental Content

Retina November 2024

Seasonal Variation in ATP-Induced Retinal Damage in the Cone-Dominant 13-Lined Ground Squirrel

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Owen R. Bowie; Hannah M. Follett; Ching Tzu Yu; Chloe Guillaume; Phyllis M. Summerfelt; Nicole Manfredonia; Jenna Grieshop; Dana K. Merriman; Sergey Tarima; Joseph Carroll
TAGS: cohort studies, diagnostic imaging, follow-up, intravitreal injections, retinal cone, scanning laser ophthalmoscopy, seasonal variation, mosaicism, injections, mosaic trial
Trans. Vis. Sci. Tech.. 2024; 13(11):5. https://doi.org/10.1167/tvst.13.11.5

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2024

Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort

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Zihan Sun; Kelsey V. Stuart; Robert N. Luben; Amy L. Auld; Nicholas G. Strouthidis; Peng T. Khaw; Hari Jayaram; Anthony P. Khawaja; Paul J. Foster; on behalf of the UK Biobank Eye and Vision Consortium
TAGS: air pollution, cohort studies, glaucoma, uk biobank
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):22. https://doi.org/10.1167/iovs.65.12.22

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2024

Glial Cell Responses and Gene Expression Dynamics in Retinas of Treated and Untreated RPE65 Mutant Dogs

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Tatyana Appelbaum; Evelyn Santana; David A. Smith; William A. Beltran; Gustavo D. Aguirre
TAGS: did not receive therapy or drug, dog, domestic, retina, rpe65 protein, neuroglia, gene expression, middle-aged adult
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):18. https://doi.org/10.1167/iovs.65.12.18

Includes: Supplemental Content

Retina October 2024

Effect of Ocular Perfusion Pressure on Incidence of Diabetic Retinopathy in Type 2 Diabetes: A Two-Year Prospective Study

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Yayi Yan; Xinyan Wu; Yuntong Li; Yiran Fan; Lingyi Li; Ching-Kit Tsui; Kaiqun Liu; Wenyong Huang; Xiaoling Liang; Andina Hu; on behalf of GDES Group
TAGS: diabetes mellitus, type 2, diabetic retinopathy, incidence, mopp protocol, perfusion, prospective studies
Trans. Vis. Sci. Tech.. 2024; 13(10):20. https://doi.org/10.1167/tvst.13.10.20

Multidisciplinary Ophthalmic Imaging October 2024

Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers

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Natasa Jeremic; Maximilian Pawloff; Dmitrii Lachinov; Stephanie Rokitansky; Matthias Hasun; Franz Weidinger; Andreas Pollreisz; Hrvoje Bogunović; Ursula Schmidt-Erfurth
TAGS: biological markers, coronary arteriosclerosis, stratification
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):15. https://doi.org/10.1167/iovs.65.12.15

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics October 2024

Statistical Model of Ocular Wavefronts With Accommodation

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María Mechó-García; María Arcas-Carbonell; Elvira Orduna-Hospital; Ana Sánchez-Cano; Norberto López-Gil; Rute J. Macedo-de-Araújo; Miguel Faria-Ribeiro; Paulo Fernandes; José Manuel González-Méijome; Jos Rozema
TAGS: models, statistical, visual accommodation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):12. https://doi.org/10.1167/iovs.65.12.12

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2024

Initial Retinal Nerve Fiber Layer Loss and Risk of Diabetic Retinopathy Over a Four-Year Period

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Xiaoying Zhong; Huangdong Li; Shaoying Tan; Shaopeng Yang; Ziyu Zhu; Wenyong Huang; Weijing Cheng; Wei Wang
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, retinal nerve fiber layer, follow-up, predictive value
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):5. https://doi.org/10.1167/iovs.65.12.5

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2024

Predictors of Discordance Between Dry Eye Symptoms and Signs: Insights From the Sjögren's International Collaborative Clinical Alliance

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Fanxiu Xiong; Benjamin F. Arnold; Thomas M. Lietman; John A. Gonzales
TAGS: dry eye syndromes, signs and symptoms, sjogren's syndrome, ocular signs and symptoms
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):3. https://doi.org/10.1167/iovs.65.12.3

Includes: Supplemental Content

Clinical and Epidemiologic Research September 2024

Visual Performance of People With Albinism Assessed With Generalizable and Adaptive AIM and FInD Methods

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Jan Skerswetat; Nicole Christie Ross; Cecilia Idman-Rait; Katie Sun; Olivia Wynn; Peter John Bex
TAGS: albinism, color, contrast sensitivity, motion, noise, psychophysics, visual acuity, vision, glare
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):34. https://doi.org/10.1167/iovs.65.11.34

Includes: Supplemental Content

Cornea & External Disease September 2024

Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

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Yuan Chang; Tianze Huang; Shan Yang; Ying Li; Di Chen
TAGS: atopic dermatitis, keratoconus, mendelian randomization analysis, genome-wide association study, datasets
Trans. Vis. Sci. Tech.. 2024; 13(9):13. https://doi.org/10.1167/tvst.13.9.13

Includes: Supplemental Content

Retina September 2024

Impact of the Coronavirus Disease 2019 Pandemic on Outpatient Visits for Diabetic Retinopathy in Japan: A Retrospective Cohort Study

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Kunihiko Hirosawa; Takenori Inomata; Yasutsugu Akasaki; Jaemyoung Sung; Alan Yee; Masao Iwagami; Ken Nagino; Yuichi Okumura; Keiichi Fujimoto; Akie Midorikawa-Inomata; Atsuko Eguchi; Hurramhon Shokirova; Kenta Fujio; Tianxiang Huang; Yuki Morooka; Hiroyuki Kobayashi; Akira Murakami; Shintaro Nakao
TAGS: cohort studies, retrospective, covid-19, diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, outpatients, pandemics, risk factors
Trans. Vis. Sci. Tech.. 2024; 13(9):6. https://doi.org/10.1167/tvst.13.9.6

Includes: Supplemental Content

Clinical and Epidemiologic Research September 2024

Prognostic Impact of Notch1 Intracellular Domain, P63, and c-MYC in Lacrimal Gland Adenoid Cystic Carcinoma

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Jiawei Zhao; Michelle D. Williams; Mike Hernandez; Grace Kuang; Hila Goldberg; Janet Fan; Jing Ning; Renata Ferrarotto; Bita Esmaeli
TAGS: adenoid cystic carcinoma, c-myc genes, lacrimal gland, notch1 gene, patient prognosis, tp63 gene, neoplasms, recurrence
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):4. https://doi.org/10.1167/iovs.65.11.4

Lens September 2024

Lens Power and Associated Factors in Nonhuman Primate Subjects: A Cross-sectional Study

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Yingting Zhu; Rui Xie; Qi Zhang; Yuan Zhang; Guitong Ye; Liangzhi Xu; Simeng Hou; Wei Liu; Zhiwei Huang; Jian Wu; Yehong Zhuo
TAGS: cross-sectional studies, eye, lens, crystalline, primates, myopia
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):2. https://doi.org/10.1167/iovs.65.11.2

Includes: Supplemental Content

Clinical and Epidemiologic Research August 2024

Long-Term Prediction and Risk Factors for Incident Visual Field Defect in Nonpathologic High Myopia

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Cong Li; Yanping Chen; Shaopeng Yang; Ruilin Xiong; Riqian Liu; Ziyu Zhu; Shida Chen; Mingguang He; Wei Wang
TAGS: myopia, visual field defects, risk factors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):43. https://doi.org/10.1167/iovs.65.10.43

Includes: Supplemental Content

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Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China

Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

Potential Prognostic Protein Biomarkers in Tears From Noninfectious Uveitis Patients Under Biologic Treatment as a Prelude to Personalized Medicine

Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

Seasonal Variation in ATP-Induced Retinal Damage in the Cone-Dominant 13-Lined Ground Squirrel

Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort

Glial Cell Responses and Gene Expression Dynamics in Retinas of Treated and Untreated RPE65 Mutant Dogs

Effect of Ocular Perfusion Pressure on Incidence of Diabetic Retinopathy in Type 2 Diabetes: A Two-Year Prospective Study

Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers

Statistical Model of Ocular Wavefronts With Accommodation

Initial Retinal Nerve Fiber Layer Loss and Risk of Diabetic Retinopathy Over a Four-Year Period

Predictors of Discordance Between Dry Eye Symptoms and Signs: Insights From the Sjögren's International Collaborative Clinical Alliance

Visual Performance of People With Albinism Assessed With Generalizable and Adaptive AIM and FInD Methods

Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

Impact of the Coronavirus Disease 2019 Pandemic on Outpatient Visits for Diabetic Retinopathy in Japan: A Retrospective Cohort Study

Prognostic Impact of Notch1 Intracellular Domain, P63, and c-MYC in Lacrimal Gland Adenoid Cystic Carcinoma

Lens Power and Associated Factors in Nonhuman Primate Subjects: A Cross-sectional Study

Long-Term Prediction and Risk Factors for Incident Visual Field Defect in Nonpathologic High Myopia

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