Clinical and Epidemiologic Research

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Artificial Intelligence April 2024

Retinal Fractal Dimension Is a Potential Biomarker for Systemic Health—Evidence From a Mixed-Age, Primary-Care Population

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Justin Engelmann; Stephanie Kearney; Alice McTrusty; Greta McKinlay; Miguel O. Bernabeu; Niall Strang
TAGS: biological markers, fractals, health, image quality, primary health care
Trans. Vis. Sci. Tech.. 2024; 13(4):19. https://doi.org/10.1167/tvst.13.4.19

Includes: Supplemental Content

Genetics April 2024

Longitudinal Natural History Study of Visual Function in Bietti Crystalline Dystrophy: Implications for Early Intervention

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Xiaoxu Han; Huajin Li; Dingding Zhang; Hui Li; Xuan Zou; Ruifang Sui
TAGS: crystal structure, early intervention (education), natural history, vision, linear regression
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):25. https://doi.org/10.1167/iovs.65.4.25

Anatomy and Pathology/Oncology April 2024

Histologic and Genomic Analysis of Conjunctival SCC in African and American Cohorts Reveal UV Light and HPV Signatures and High Tumor Mutation Burden

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Frederico O. Gleber-Netto; Priyadharsini Nagarajan; Oded Sagiv; Curtis R. Pickering; Neil Gross; Jing Ning; Melisachew M. Yeshi; Yonas Mitku; Michael T. Tetzlaff; Bita Esmaeli
TAGS: cohort studies, conjunctiva, genome, human papillomavirus, mutation, neoplasms, tumor mutation burden, ultraviolet rays, squamous cell carcinoma
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):24. https://doi.org/10.1167/iovs.65.4.24

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2024

Early Single-Examination Optical Coherence Tomography Biomarkers for Treatment-Requiring Retinopathy of Prematurity

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Xi Chen; Shwetha Mangalesh; Jocelyn He; Katrina P. Winter; Vincent Tai; Cynthia A. Toth; Gui-Shuang Ying
TAGS: biological markers, eye, macular edema, optical coherence tomography, retinopathy of prematurity, diagnostic imaging, infant, premature, infant, gestational age, ratio of arterial oxygen tension to inspired oxygen fraction
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):21. https://doi.org/10.1167/iovs.65.4.21

Includes: Supplemental Content

Artificial Intelligence April 2024

Code-Free Machine Learning Approach for EVO-ICL Vault Prediction: A Retrospective Two-Center Study

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Daeun Shin; Hannuy Choi; Dongyoung Kim; Jaekyung Park; Tae Keun Yoo; Kyungmin Koh
TAGS: machine learning, postoperative care, retrospective studies, eye, random forest, surgical procedures, operative, implantation procedure
Trans. Vis. Sci. Tech.. 2024; 13(4):4. https://doi.org/10.1167/tvst.13.4.4

Includes: Supplemental Content

Clinical and Epidemiologic Research March 2024

Macular Curvature in Adults Born Preterm With and Without ROP: Results from the Gutenberg Prematurity Eye Study

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Achim Fieß; Christin Volmering; Sandra Gißler; Eva Mildenberger; Michael S. Urschitz; Panagiotis Laspas; Bernhard Stoffelns; Norbert Pfeiffer; Alexander K. Schuster
TAGS: adult, eye, infant, premature, premature birth, perinatal period, birth weight, medical history
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):39. https://doi.org/10.1167/iovs.65.3.39

Includes: Supplemental Content

Clinical and Epidemiologic Research March 2024

The Association Between Metformin Use and New-Onset ICD Coding of Geographic Atrophy

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John Moir; Max J. Hyman; Reem Gonnah; Andrea Flores; Seenu M. Hariprasad; Dimitra Skondra
TAGS: age-related macular degeneration, nonexudative, metformin, diabetes mellitus, diabetes mellitus, type 2
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):23. https://doi.org/10.1167/iovs.65.3.23

Includes: Supplemental Content

Clinical and Epidemiologic Research March 2024

Longitudinal Changes in Choroidal Thickness Varied With Refractive Progression in Myopic and Non-Myopic Children: A Two-Year Cohort Study

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Menglu Shen; Xiaotong Han; Yan Yang; Hailu Huang; Jinen Hou; Ling Jin; Xinping Yu; Yangfa Zeng; Mingguang He
TAGS: child, cohort studies, myopia
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):17. https://doi.org/10.1167/iovs.65.3.17

Includes: Supplemental Content

Clinical and Epidemiologic Research March 2024

Evaluation of the Observational Associations and Shared Genetics Between Glaucoma With Depression and Anxiety

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Xiayin Zhang; Yingying Liang; Yu Huang; Shunming Liu; Qinyi Li; Shan Wang; Guanrong Wu; Zijing Du; Yaxin Wang; Jinghui Wang; Yunyan Hu; Siwen Zang; Yijun Hu; Xianwen Shang; Xueli Zhang; Lei Zhang; Andrew Brown; Zhuoting Zhu; Mingguang He; Honghua Yu
TAGS: anxiety, depressive disorders, genetics, glaucoma, mental disorders
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):12. https://doi.org/10.1167/iovs.65.3.12

Includes: Supplemental Content

Public Health February 2024

Disparities in Eye Care Utilization Among Refugee and Migrant Populations

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Ivan A. Copado; Shahin Hallaj; Bharanidharan Radha Saseendrakumar; Sally L. Baxter
TAGS: eye care, health disparity, refugees, cohort studies
Trans. Vis. Sci. Tech.. 2024; 13(2):14. https://doi.org/10.1167/tvst.13.2.14

Includes: Supplemental Content

Retina February 2024

Temporal-to-Nasal Macular Ganglion Cell and Inner Plexiform Layer Ratios in a Large Adult Twin Cohort: Correlations With Age and Heritability

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Zakariya A. Jarrar; Khaldoon O. Al-Nosairy; Xiaofan Jiang; Ali Lamin; Dominic Wong; Abdus S. Ansari; Katie M. Williams; Sobha Sivaprasad; Michael B. Hoffmann; Pirro G. Hysi; Christopher J. Hammond; Omar A. Mahroo
TAGS: adult, cohort studies, ganglia, nose, twins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):26. https://doi.org/10.1167/iovs.65.2.26

Refractive Intervention January 2024

Ultra-Widefield Imaging of the Retinal Macrovasculature in Parkinson Disease Versus Controls With Normal Cognition Using Alpha-Shapes Analysis

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Justin P. Ma; Cason B. Robbins; Emma Pead; Sarah McGrory; Charlene Hamid; Dilraj S. Grewal; Burton L. Scott; Emanuele Trucco; Tom J. MacGillivray; Sharon Fekrat
TAGS: cognition, diagnostic imaging, parkinson disease, shape, retinal vessels, eye, vasculature
Trans. Vis. Sci. Tech.. 2024; 13(1):15. https://doi.org/10.1167/tvst.13.1.15

Genetics January 2024

Clinical and Genetic Landscape of Ectopia Lentis Based on a Cohort of Patients From 156 Families

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Dongwei Guo; Shiqiang Li; Xueshan Xiao; Yi Jiang; Yingwei Wang; Guangming Jin; Junwen Wang; Jiamin Ouyang; Xiaoyun Jia; Wenmin Sun; Panfeng Wang; Danying Zheng; Qingjiong Zhang
TAGS: cohort studies, ectopia lentis, family, fibrillin-1, genetics, genes, genotype, phenotype
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):20. https://doi.org/10.1167/iovs.65.1.20

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2024

Age-Related Macular Degeneration Choroidal Vascular Distribution Characteristics Based on Indocyanine Green Angiography

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Ke Wu; Jiayi Wu; Jing Yao; Rundong Song; Ruihua Jing; Wenpeng Li; Xuan Wang; Nianjia Wang; Yuping Zheng; Liang Yao
TAGS: age-related macular degeneration, indocyanine green angiography, trunk structure, eye, choroidal artery, angiogram
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):16. https://doi.org/10.1167/iovs.65.1.16

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2024

Change of Intraocular Pressure Over 5 Years and its Relationship to Cardiovascular Parameters: Results From the Gutenberg Health Study

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Alica Hartmann; Ida Scholz; Esther M. Hoffmann; Alicja Strzalkowska; Karl J. Lackner; Thomas Münzel; Felix S. Wicke; Irene Schmidtmann; Oliver Tüscher; Jörn M. Schattenberg; Stavros Konstantinides; Philipp S. Wild; Norbert Pfeiffer; Alexander K. Schuster
TAGS: health, intraocular pressure, body mass index procedure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):12. https://doi.org/10.1167/iovs.65.1.12

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2024

Smoking, Corneal Biomechanics, and Glaucoma: Results From Two Large Population-Based Cohorts

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Kelsey V. Stuart; Kian M. Madjedi; Robert N. Luben; Mahantesh I. Biradar; Siegfried K. Wagner; Alasdair N. Warwick; Zihan Sun; Pirro G. Hysi; Mark J. Simcoe; Paul J. Foster; Anthony P. Khawaja; on behalf of the Modifiable Risk Factors for Glaucoma Collaboration and the UK Biobank Eye and Vision Consortium
TAGS: biomechanics, cohort studies, cornea, glaucoma, smoking, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):11. https://doi.org/10.1167/iovs.65.1.11

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2023

Eye Size and Shape in Relation to Refractive Error in Children: A Magnetic Resonance Imaging Study

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Sander C. M. Kneepkens; Kasper Marstal; Jan-Roelof Polling; Vincent W. V. Jaddoe; Meike W. Vernooij; Dirk H. J. Poot; Caroline C. W. Klaver; J. Willem L. Tideman
TAGS: child, eye, magnetic resonance imaging, refractive errors, shape, biometry, optics
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):41. https://doi.org/10.1167/iovs.64.15.41

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2023

Long-Term Axial Length Shortening in Myopic Orthokeratology: Incident Probability, Time Course, and Influencing Factors

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Yin Hu; Xiaohu Ding; Jinyun Jiang; Mengting Yu; Linxing Chen; Zhou Zhai; Hening Zhang; Binglan Fang; Huarong Wang; Shuiming Yu; Mingguang He; Junwen Zeng; Yangfa Zeng; Xiao Yang
TAGS: orthokeratology, time factors
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):37. https://doi.org/10.1167/iovs.64.15.37

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2023

Parapapillary β BM and γ Zones Played Different Roles in Axial Elongation Among Young Adolescents Using Optical Coherence Tomography

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Yin Guo; Jiayan Li; Feifei Tian; Rui Hou; Lijuan Liu; Jiali Duan; Ang Ji; Youxin Wang; Xiuhua Guo; Deqiang Zheng; Wei Wang; Lijuan Wu
TAGS: adolescent, eye, optic disk, optical coherence tomography, follow-up, myopia, choroid
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):34. https://doi.org/10.1167/iovs.64.15.34

Includes: Supplemental Content

Artificial Intelligence December 2023

Risk Stratification for Diabetic Retinopathy Screening Order Using Deep Learning: A Multicenter Prospective Study

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Ashish Bora; Richa Tiwari; Pinal Bavishi; Sunny Virmani; Rayman Huang; Ilana Traynis; Greg S. Corrado; Lily Peng; Dale R. Webster; Avinash V. Varadarajan; Warisara Pattanapongpaiboon; Reena Chopra; Paisan Ruamviboonsuk
TAGS: deep learning, diabetic retinopathy screening, hemoglobin a, glycosylated, prospective studies, screening, stratification, diabetes mellitus, diabetes mellitus, type 2
Trans. Vis. Sci. Tech.. 2023; 12(12):11. https://doi.org/10.1167/tvst.12.12.11

Includes: Supplemental Content

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Retinal Fractal Dimension Is a Potential Biomarker for Systemic Health—Evidence From a Mixed-Age, Primary-Care Population

Longitudinal Natural History Study of Visual Function in Bietti Crystalline Dystrophy: Implications for Early Intervention

Histologic and Genomic Analysis of Conjunctival SCC in African and American Cohorts Reveal UV Light and HPV Signatures and High Tumor Mutation Burden

Early Single-Examination Optical Coherence Tomography Biomarkers for Treatment-Requiring Retinopathy of Prematurity

Code-Free Machine Learning Approach for EVO-ICL Vault Prediction: A Retrospective Two-Center Study

Macular Curvature in Adults Born Preterm With and Without ROP: Results from the Gutenberg Prematurity Eye Study

The Association Between Metformin Use and New-Onset ICD Coding of Geographic Atrophy

Longitudinal Changes in Choroidal Thickness Varied With Refractive Progression in Myopic and Non-Myopic Children: A Two-Year Cohort Study

Evaluation of the Observational Associations and Shared Genetics Between Glaucoma With Depression and Anxiety

Disparities in Eye Care Utilization Among Refugee and Migrant Populations

Temporal-to-Nasal Macular Ganglion Cell and Inner Plexiform Layer Ratios in a Large Adult Twin Cohort: Correlations With Age and Heritability

Ultra-Widefield Imaging of the Retinal Macrovasculature in Parkinson Disease Versus Controls With Normal Cognition Using Alpha-Shapes Analysis

Clinical and Genetic Landscape of Ectopia Lentis Based on a Cohort of Patients From 156 Families

Age-Related Macular Degeneration Choroidal Vascular Distribution Characteristics Based on Indocyanine Green Angiography

Change of Intraocular Pressure Over 5 Years and its Relationship to Cardiovascular Parameters: Results From the Gutenberg Health Study

Smoking, Corneal Biomechanics, and Glaucoma: Results From Two Large Population-Based Cohorts

Eye Size and Shape in Relation to Refractive Error in Children: A Magnetic Resonance Imaging Study

Long-Term Axial Length Shortening in Myopic Orthokeratology: Incident Probability, Time Course, and Influencing Factors

Parapapillary β BM and γ Zones Played Different Roles in Axial Elongation Among Young Adolescents Using Optical Coherence Tomography

Risk Stratification for Diabetic Retinopathy Screening Order Using Deep Learning: A Multicenter Prospective Study

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