Retina

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Retina November 2024

Automated Detection of Drusenoid Pigment Epithelial Detachments From Spectral-Domain Optical Coherence Tomography in Patients With AMD

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Souvick Mukherjee; Cameron Duic; Tharindu De Silva; Tiarnan D. L. Keenan; Alisa T. Thavikulwat; Emily Y. Chew; Catherine Cukras
TAGS: drusen, retinal pigment epithelial detachment, spectral domain-optical coherence tomography, reading (activity), eye
Trans. Vis. Sci. Tech.. 2024; 13(11):25. https://doi.org/10.1167/tvst.13.11.25

Includes: Supplemental Content

Retina November 2024

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

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Nicole A. Muench; Heather M. Schmitt; Cassandra L. Schlamp; An-Jey A. Su; Kia Washington; Robert W. Nickells
TAGS: cryopreservation, eye, mice
Trans. Vis. Sci. Tech.. 2024; 13(11):24. https://doi.org/10.1167/tvst.13.11.24

Includes: Supplemental Content

Retina November 2024

Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration

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Elham Sadeghi; Nicola Valsecchi; Mohammed Nasar Ibrahim; Katherine Du; Elli Davis; Sandeep Chandra Bollepalli; Kiran Kumar Vupparaboina; Jose Alain Sahel; Jay Chhablani
TAGS: age-related macular degeneration, cardiovascular imaging, cortical blindness, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):39. https://doi.org/10.1167/iovs.65.13.39

Retina November 2024

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

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Akishi Onishi; Yuji Tsunekawa; Michiko Mandai; Aiko Ishimaru; Yoko Ohigashi; Junki Sho; Kazushi Yasuda; Keiichiro Suzuki; Juan Carlos Izpisua Belmonte; Fumio Matsuzaki; Masayo Takahashi
TAGS: genes, genome editing, mice, retinitis pigmentosa, rhodopsin, rod photoreceptors, donors, plasmids, electroporation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):38. https://doi.org/10.1167/iovs.65.13.38

Includes: Supplemental Content

Cornea & External Disease November 2024

A New Method for Lateral Visualization of the Primary Cilia on the Surfaces of Cells Cultured on White Glass Rods

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Hidetoshi Tanioka; Hideto Deguchi; Shigeru Kinoshita; Chie Sotozono
TAGS: cilia, glass, rod photoreceptors, scirrhous adenocarcinoma, chronic exertional compartment syndrome
Trans. Vis. Sci. Tech.. 2024; 13(11):19. https://doi.org/10.1167/tvst.13.11.19

Includes: Multimedia, Supplemental Content

Low Vision Rehabilitation November 2024

Development and Psychometric Assessment of a Chinese Version of the Ultra-Low Vision Visual Functioning Questionnaire-50

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Jing Cong; Xinyuan Wu; Chunqiong Dong; Jing Wang; Chenli Feng; Gechun Wang; Yiting Wu; Gislin Dagnelie; Jinhui Dai; Yuanzhi Yuan
TAGS: chinese (other dialects), chinese people, psychometrics, questionnaires, vision, rasch model
Trans. Vis. Sci. Tech.. 2024; 13(11):20. https://doi.org/10.1167/tvst.13.11.20

Includes: Supplemental Content

Retina November 2024

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

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Saman Ebrahimi; Phillip Bedggood; Yifu Ding; Andrew Metha; Prosenjit Bagchi
TAGS: blood capillaries, blood cells, computer simulation, fluid flow, hematocrit, hemodynamics, microcirculation, microvascular network, velocity, retail clinics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):37. https://doi.org/10.1167/iovs.65.13.37

Includes: Multimedia, Supplemental Content

Retina November 2024

High Intraocular Concentration of Fibrinogen Regulates Retinal Function Via the ICAM-1 Pathway

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Yasuyuki Sotani; Hisanori Imai; Hiroko Yamada; Akiko Miki; Sentaro Kusuhara; Makoto Nakamura
TAGS: fibrinogen, intercellular adhesion molecule 1, mass or substance concentration per volume, intravitreal injections, mice, antibodies
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):34. https://doi.org/10.1167/iovs.65.13.34

Retina November 2024

Associations of Retinal Vessel Geometry and Optical Coherence Tomography Angiography Metrics With Choroidal Metrics in Diabetic Retinopathy

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Dae Joong Ma; Seong Mi Kim; Ji Min Choi
TAGS: angiogram, chief complaint, choroid diseases, cortical blindness, diabetes mellitus, diabetic retinopathy, optical coherence tomography, retinal vessels, cardiovascular imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):31. https://doi.org/10.1167/iovs.65.13.31

Includes: Supplemental Content

Retina November 2024

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

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Huan Liu; Feiyan Wang; Ziqing Hu; Jing Wei
TAGS: diabetic retinopathy, drug delivery systems, mendelian randomization analysis, plasma proteins, proteins
Trans. Vis. Sci. Tech.. 2024; 13(11):17. https://doi.org/10.1167/tvst.13.11.17

Includes: Supplemental Content

Retina November 2024

Patient-Reported Outcomes in RLBP1 Retinal Dystrophy: Longitudinal Assessment in a Prospective Natural History Study

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James Whelan; Jane Green; Marie Burstedt; Erin Greco; Xiao Ni; Claudio Spera; Anmol Mullins; Jean-Yves Deslandes; Zhenzhong Su; Michael Wald; Cynthia L. Grosskreutz; Guillaume Normand; Arnaud Charil; Darlene Lu; Kalliopi Stasi; Karen Holopigian
TAGS: natural history, patient self-report, pik3ca-related overgrowth spectrum, questionnaires, rasch model, retinal dystrophies, vision, significance
Trans. Vis. Sci. Tech.. 2024; 13(11):16. https://doi.org/10.1167/tvst.13.11.16

Includes: Supplemental Content

Retina November 2024

Interpericyte Tunneling Nanotubes Are Nonuniformly Distributed in the Human Macula

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Martin Hein; Hassanain Qambari; Paula Yu; Dao-Yi Yu; Chandrakumar Balaratnasingam
TAGS: macula lutea, blood capillaries, pericytes, donors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):28. https://doi.org/10.1167/iovs.65.13.28

Includes: Multimedia, Supplemental Content

Genetics November 2024

Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort

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Yufei Xu; Xiao Liu; Nan Wu; Yanling Long; Jiayun Ren; Yu Wang; Xinyi Su; Zengping Liu; Yu Fujinami-Yokokawa; Kaoru Fujinami; Fang Chen; Xiaohong Meng; Yong Liu
TAGS: cohort studies, crystal structure, disease progression, eye, fovea centralis, longitudinal studies, genotype, vision, blindness, mutation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):27. https://doi.org/10.1167/iovs.65.13.27

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging November 2024

Evaluating the Impact of Retinal Vessel Segmentation Metrics on Retest Reliability in a Clinical Setting: A Comparative Analysis Using AutoMorph

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Samuel D. Giesser; Ferhat Turgut; Amr Saad; Jay R. Zoellin; Chiara Sommer; Yukun Zhou; Siegfried K. Wagner; Pearse A. Keane; Matthias Becker; Delia Cabrera DeBuc; Gábor Márk Somfai
TAGS: biological markers, image quality, reliability, retinal vessels
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):24. https://doi.org/10.1167/iovs.65.13.24

Includes: Supplemental Content

Retina November 2024

Choroidal Thickness and Visual Acuity in High Myopia Without Myopic Maculopathy: Insights From a Chinese Population Study

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Yueye Wang; Decai Wang; Qiuxia Yin; Jiayong Li; Zhixi Li; Mingguang He
TAGS: macular disorders, myopia, population studies, vision, visual acuity, chinese (other dialects), chinese people
Trans. Vis. Sci. Tech.. 2024; 13(11):9. https://doi.org/10.1167/tvst.13.11.9

Includes: Supplemental Content

Retinal Cell Biology November 2024

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease

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Jimin Han; Sueanne Chear; Jana Talbot; Vicki Swier; Clarissa Booth; Cheyenne Reuben-Thomas; Sonal Dalvi; Jill M. Weimer; Alex W. Hewitt; Anthony L. Cook; Ruchira Singh
TAGS: autofluorescence, phagocytosis, photoreceptors, platypnea orthodeoxia syndrome, retinal pigment cell, tissue degeneration, genetics, lipofuscin, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):23. https://doi.org/10.1167/iovs.65.13.23

Includes: Supplemental Content

Visual Neuroscience November 2024

The Electroretinogram I-Wave, a Component Originating in the Retinal OFF-Pathway, Associates With a Myopia Genetic Risk Polymorphism

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Zihe Xu; Jit Kai Tan; Krishnika Vetrivel; Xiaofan Jiang; Shaun M. Leo; Taha Bhatti; Ambreen Tariq; Andrew R. Webster; Anthony G. Robson; Christopher J. Hammond; Pirro G. Hysi; Omar A. Mahroo
TAGS: electroretinography, genetic risk, myopia, polymorphism
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):21. https://doi.org/10.1167/iovs.65.13.21

Includes: Supplemental Content

Retina November 2024

Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging

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Jacqueline Fröhlich; Marco Cattaneo; Philippe Valmaggia; Peter M. Maloca; Konstantin Gugleta; Leopold Schmetterer; Hendrik P.N. Scholl; Giacomo Calzetti
TAGS: laser speckle contrast imaging, optic disk, perfusion, vascular flow, eye, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2024; 13(11):8. https://doi.org/10.1167/tvst.13.11.8

Includes: Supplemental Content

Artificial Intelligence November 2024

SLOctolyzer: Fully Automatic Analysis Toolkit for Segmentation and Feature Extracting in Scanning Laser Ophthalmoscopy Images

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Jamie Burke; Samuel Gibbon; Justin Engelmann; Adam Threlfall; Ylenia Giarratano; Charlene Hamid; Stuart King; Ian J. C. MacCormick; Thomas J. MacGillivray
TAGS: optic disk, scanning laser ophthalmoscopy, fovea centralis, datasets, pixel
Trans. Vis. Sci. Tech.. 2024; 13(11):7. https://doi.org/10.1167/tvst.13.11.7

Includes: Supplemental Content

Retina November 2024

Seasonal Variation in ATP-Induced Retinal Damage in the Cone-Dominant 13-Lined Ground Squirrel

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Owen R. Bowie; Hannah M. Follett; Ching Tzu Yu; Chloe Guillaume; Phyllis M. Summerfelt; Nicole Manfredonia; Jenna Grieshop; Dana K. Merriman; Sergey Tarima; Joseph Carroll
TAGS: cohort studies, diagnostic imaging, follow-up, intravitreal injections, retinal cone, scanning laser ophthalmoscopy, seasonal variation, mosaicism, injections, mosaic trial
Trans. Vis. Sci. Tech.. 2024; 13(11):5. https://doi.org/10.1167/tvst.13.11.5

Includes: Supplemental Content

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Automated Detection of Drusenoid Pigment Epithelial Detachments From Spectral-Domain Optical Coherence Tomography in Patients With AMD

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

A New Method for Lateral Visualization of the Primary Cilia on the Surfaces of Cells Cultured on White Glass Rods

Development and Psychometric Assessment of a Chinese Version of the Ultra-Low Vision Visual Functioning Questionnaire-50

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

High Intraocular Concentration of Fibrinogen Regulates Retinal Function Via the ICAM-1 Pathway

Associations of Retinal Vessel Geometry and Optical Coherence Tomography Angiography Metrics With Choroidal Metrics in Diabetic Retinopathy

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

Patient-Reported Outcomes in RLBP1 Retinal Dystrophy: Longitudinal Assessment in a Prospective Natural History Study

Interpericyte Tunneling Nanotubes Are Nonuniformly Distributed in the Human Macula

Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort

Evaluating the Impact of Retinal Vessel Segmentation Metrics on Retest Reliability in a Clinical Setting: A Comparative Analysis Using AutoMorph

Choroidal Thickness and Visual Acuity in High Myopia Without Myopic Maculopathy: Insights From a Chinese Population Study

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease

The Electroretinogram I-Wave, a Component Originating in the Retinal OFF-Pathway, Associates With a Myopia Genetic Risk Polymorphism

Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging

SLOctolyzer: Fully Automatic Analysis Toolkit for Segmentation and Feature Extracting in Scanning Laser Ophthalmoscopy Images

Seasonal Variation in ATP-Induced Retinal Damage in the Cone-Dominant 13-Lined Ground Squirrel

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