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Retina January 2025

A Penetrable AAV2 Capsid Variant for Efficient Intravitreal Gene Delivery to the Retina

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Xiaoyu He; Yidian Fu; Yangfan Xu; Liang Ma; Peiwei Chai; Hanhan Shi; Yizheng Yao; Shengfang Ge; Renbing Jia; Xuyang Wen; Zhi Yang; Xianqun Fan

Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):6. https://doi.org/10.1167/iovs.66.1.6

Includes: Supplemental Content

Retinal Cell Biology January 2025

Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy

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Ao-Wang Qiu; Ning-Yu Wang; Wen-Jie Yin; Zhao-Qi Zhu; Qing-Huai Liu; Wei-Wei Zhang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):1. https://doi.org/10.1167/iovs.66.1.1

Clinical and Epidemiologic Research January 2025

Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults

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Yanping Chen; Ruilin Xiong; Jian Zhang; Shaopeng Yang; Huangdong Li; Ziyu Zhu; Peiyuan Wang; Mingguang He; Yingfeng Zheng; Wei Wang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):2. https://doi.org/10.1167/iovs.66.1.2

Includes: Supplemental Content

Retina January 2025

Blue Light Damages Retinal Ganglion Cells Via Endoplasmic Reticulum Stress and Autophagy in Chickens

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Deng Pan; Ge Hu; Jiayue Li; Zixu Wang; Yaoxing Chen; Jing Cao

Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):3. https://doi.org/10.1167/iovs.66.1.3

Includes: Supplemental Content

Retina January 2025

Deep Learning–Based SD-OCT Layer Segmentation Quantifies Outer Retina Changes in Patients With Biallelic RPE65 Mutations Undergoing Gene Therapy

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German Pinedo-Diaz; Birgit Lorenz; Sandrine H. Künzel; Sarah Thiele; Susana Ortega-Cisneros; Eduardo Bayro Corrochano; Frank G. Holz; Alexander Effland

Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):5. https://doi.org/10.1167/iovs.66.1.5

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2025

Validating Rules for Defining No Improvement of Visual Acuity in Childhood Amblyopia

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Rui Wu; Ruth E. Manny; Jonathan M. Holmes; B. Michele Melia; Zhuokai Li; David K. Wallace; Eileen E. Birch; Raymond T. Kraker; Susan A. Cotter; on behalf of the Pediatric Eye Disease Investigator Group

Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):4. https://doi.org/10.1167/iovs.66.1.4

Includes: Supplemental Content

Article January 2025

Impaired visual perceptual accuracy in the upper visual field induces asymmetric performance in position estimation for falling and rising objects

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Takashi Hirata; Nobuyuki Kawai
TAGS: visual fields, motion
Journal of Vision. 2025; 25(1):1. https://doi.org/10.1167/jov.25.1.1

Low Vision Rehabilitation January 2025

How People With Vision Impairment Use Their Gaze to Hit a Ball

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Ward Nieboer; Carin M. Svensen; Kjell van Paridon; Debbie Van Biesen; David L. Mann
TAGS: gaze, visual impairment, eye, peripheral vision
Trans. Vis. Sci. Tech.. 2025; 14(1):1. https://doi.org/10.1167/tvst.14.1.1

Retina December 2024

Real-World Outcomes After Switch From Aflibercept to Faricimab in Eyes With Diabetic Macular Edema

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Kim Lien Huber; Heiko Stino; Irene Steiner; Philipp Fuchs; Felix Goldbach; Julia Mai; Bianca S. Gerendas; Katharina Kriechbaum; Ursula Schmidt-Erfurth; Andreas Pollreisz
TAGS: aflibercept, diabetic macular edema, eye, faricimab, injections, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):46. https://doi.org/10.1167/iovs.65.14.46

Includes: Supplemental Content

Retina December 2024

Topographical Quantification of Hyper-Reflective Foci May Predict the Development of Macular Atrophy in Patients With Neovascular Age-Related Macular Degeneration

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Pasquale Viggiano; Giacomo Boscia; Giuseppe Giannaccare; Michele Santoro; Giovanni Petrara; Ciro Borriello; Enrico Borrelli; Michele Reibaldi; Maria Oliva Grassi; Giovanni Alessio; Francesco Boscia
TAGS: atrophoderma maculatum, exudative age-related macular degeneration, retina, anti-vascular endothelial growth factor therapy, macular neovascularization, follow-up visit
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):45. https://doi.org/10.1167/iovs.65.14.45

Erratum December 2024

Erratum in: Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

PDF

Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):44. https://doi.org/10.1167/iovs.65.14.44

Retina December 2024

Association of Metabolomics With Incidence of Age-Related Macular Degeneration: The UK Biobank Study

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Jun Yu; Yuzhou Zhang; Mary Ho; Xiu Juan Zhang; Ka Wai Kam; Alvin L. Young; Chi Pui Pang; Clement C. Tham; Jason C. Yam; Li Jia Chen
TAGS: age-related macular degeneration, incidence, metabolites, metabolomics, uk biobank, biological markers, polygenic risk score, lipids
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):43. https://doi.org/10.1167/iovs.65.14.43

Includes: Supplemental Content

Editorial December 2024

Reviewers

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TAGS: bsnd gene, gangs, happiness, laparoscopic uterosacral nerve ablation, reading (activity), tolnaftate, acetylcholine, achondroplasia, camurati-engelmann syndrome, e-selectin
Trans. Vis. Sci. Tech.. 2024; 13(12):38. https://doi.org/10.1167/tvst.13.12.38

Retina December 2024

The Effects of Anti-Vascular Endothelial Growth Factor Loading Injections on Retinal Microvasculature in Diabetic Macular Edema

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Kiyoung Kim; Junwoo Lee; Seung-Young Yu
TAGS: anti-vascular endothelial growth factor therapy, diabetic macular edema, endothelial growth factors, injections, retinal vasculature, nasopharyngeal aspirate
Trans. Vis. Sci. Tech.. 2024; 13(12):37. https://doi.org/10.1167/tvst.13.12.37

Lens December 2024

Acoustic Radiation Force Optical Coherence Elastography of the Crystalline Lens: Safety

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Christian Zevallos-Delgado; Taye Tolu Mekonnen; Chaitanya Duvvuri; Leana Rohman; Justin Schumacher; Manmohan Singh; Salavat R. Aglyamov; Michael D. Twa; Jean-Marie Parel; Giuliano Scarcelli; Fabrice Manns; Kirill V. Larin
TAGS: acoustics, elasticity imaging techniques, lens, crystalline, optics, radiation, safety
Trans. Vis. Sci. Tech.. 2024; 13(12):36. https://doi.org/10.1167/tvst.13.12.36

Editorial December 2024

Reviewers

PDF

TAGS: angiotensin receptor-neprilysin inhibitors, basil, cataract-alopecia-sclerodactyly syndrome, chad, chin, christianity, happiness, ilex, iris, love
Journal of Vision. 2024; 24(13):16. https://doi.org/10.1167/jov.24.13.16

Editorial December 2024

Reviewers

PDF

TAGS: acetylcholine, achondroplasia, arthritis, juvenile rheumatoid, betula, christianity, encephalomyelitis, acute disseminated, esters, gastroesophageal reflux disease, glycogen storage disease type iv, krypton
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):42. https://doi.org/10.1167/iovs.65.14.42

Review December 2024

Functional Roles of Pigment Epithelium-Derived Factor in Retinal Degenerative and Vascular Disorders: A Scoping Review

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Thomas Stax Jakobsen; Rikke L. Adsersen; Anne Louise Askou; Thomas J. Corydon
TAGS: angiogenesis, animal model, choroidal neovascularization, epithelium, neuroprotective effect, peptides, pigment, retina, retinal degeneration, retinal diseases
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):41. https://doi.org/10.1167/iovs.65.14.41

Includes: Supplemental Content

Retina December 2024

Mettl3 -Mediated m 6 A Modification is Essential for Visual Function and Retinal Photoreceptor Survival

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Xiaoyan Jiang; Kuanxiang Sun; Yudi Fan; Qianchun Xiang; Rong Zou; Yeming Yang; Xianjun Zhu; Wenjing Liu
TAGS: mice, photoreceptors, proteins, rod photoreceptors, vision, retina, retinal cone, western blotting, candidate disease gene
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):40. https://doi.org/10.1167/iovs.65.14.40

Includes: Supplemental Content

Retina December 2024

Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy

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Dhavamani Sugasini; Poorna C. R. Yalagala; Jason C. Park; Guangying Ma; Zeenat Farooq; Basma Baccouche; Onkar B. Sawant; J. Jason McAnany; Xincheng Yao; Andrius Kazlauskas; Brian T. Layden; Papasani V. Subbaiah
TAGS: diabetes mellitus, diabetic retinopathy, fatty acids, mice, retina, docosahexaenoic acids, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):39. https://doi.org/10.1167/iovs.65.14.39

Includes: Supplemental Content

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A Penetrable AAV2 Capsid Variant for Efficient Intravitreal Gene Delivery to the Retina

Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy

Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults

Blue Light Damages Retinal Ganglion Cells Via Endoplasmic Reticulum Stress and Autophagy in Chickens

Deep Learning–Based SD-OCT Layer Segmentation Quantifies Outer Retina Changes in Patients With Biallelic RPE65 Mutations Undergoing Gene Therapy

Validating Rules for Defining No Improvement of Visual Acuity in Childhood Amblyopia

Impaired visual perceptual accuracy in the upper visual field induces asymmetric performance in position estimation for falling and rising objects

How People With Vision Impairment Use Their Gaze to Hit a Ball

Real-World Outcomes After Switch From Aflibercept to Faricimab in Eyes With Diabetic Macular Edema

Topographical Quantification of Hyper-Reflective Foci May Predict the Development of Macular Atrophy in Patients With Neovascular Age-Related Macular Degeneration

Erratum in: Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

Association of Metabolomics With Incidence of Age-Related Macular Degeneration: The UK Biobank Study

Reviewers

The Effects of Anti-Vascular Endothelial Growth Factor Loading Injections on Retinal Microvasculature in Diabetic Macular Edema

Acoustic Radiation Force Optical Coherence Elastography of the Crystalline Lens: Safety

Reviewers

Reviewers

Functional Roles of Pigment Epithelium-Derived Factor in Retinal Degenerative and Vascular Disorders: A Scoping Review

Mettl3 -Mediated m 6 A Modification is Essential for Visual Function and Retinal Photoreceptor Survival

Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy

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